Raw content of Bio::SeqFeature::Computation # $Id: Computation.pm,v 1.11 2002/10/22 07:38:41 lapp Exp $ # # BioPerl module for Bio::SeqFeature::Generic # # Cared for by mark Fiers <m.w.e.j.fiers@plant.wag-ur.nl> # # Copyright Ewan Birney, Mark Fiers # # You may distribute this module under the same terms as perl itself # POD documentation - main docs before the code =head1 NAME Bio::SeqFeature::Computation - Computation SeqFeature =head1 SYNOPSIS $feat = new Bio::SeqFeature::Computation ( -start => 10, -end => 100, -strand => -1, -primary => 'repeat', -program_name => 'GeneMark', -program_date => '12-5-2000', -program_version => 'x.y', -database_name => 'Arabidopsis', -database_date => '12-dec-2000', -computation_id => 2231, -score => { no_score => 334 } ); =head1 DESCRIPTION Bio::SeqFeature::Computation extends the Generic seqfeature object with a set of computation related fields and a more flexible set of storing more types of score and subseqfeatures. It is compatible with the Generic SeqFeature object. The new way of storing score values is similar to the tag structure in the Generic object. For storing sets of subseqfeatures the array containg the subseqfeatures is now a hash which contains arrays of seqfeatures Both the score and subSeqfeature methods can be called in exactly the same way, the value's will be stored as a 'default' score or subseqfeature. =cut #' =head1 FEEDBACK =head2 Mailing Lists User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to one of the Bioperl mailing lists. Your participation is much appreciated. bioperl-l@bioperl.org - General discussion http://bio.perl.org/MailList.html - About the mailing lists =head2 Reporting Bugs Report bugs to the Bioperl bug tracking system to help us keep track the bugs and their resolution. Bug reports can be submitted via email or the web: bioperl-bugs@bio.perl.org http://bugzilla.bioperl.org/ =head1 AUTHOR - Ewan Birney, Mark Fiers Ewan Birney E<lt>birney@sanger.ac.ukE<gt> Mark Fiers E<lt>m.w.e.j.fiers@plant.wag-ur.nlE<gt> =head1 DEVELOPERS This class has been written with an eye out of inheritance. The fields the actual object hash are: _gsf_sub_hash = reference to a hash containing sets of sub arrays _gsf_score_hash= reference to a hash for the score values =head1 APPENDIX The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _ =cut # Let the code begin... package Bio::SeqFeature::Computation; use vars qw(@ISA); use strict; use Bio::Root::Root; use Bio::SeqFeature::Generic; @ISA = qw(Bio::SeqFeature::Generic); sub new { my ( $class, @args) = @_; my $self = $class->SUPER::new(@args); my ( $computation_id, $program_name, $program_date, $program_version, $database_name, $database_date, $database_version) = $self->_rearrange([qw(COMPUTATION_ID PROGRAM_NAME PROGRAM_DATE PROGRAM_VERSION DATABASE_NAME DATABASE_DATE DATABASE_VERSION )],@args); $program_name && $self->program_name($program_name); $program_date && $self->program_date($program_date); $program_version && $self->program_version($program_version); $database_name && $self->database_name($database_name); $database_date && $self->database_date($database_date); $database_version && $self->database_version($database_version); $computation_id && $self->computation_id($computation_id); return $self; } =head2 has_score Title : has_score Usage : $value = $self->has_score('some_score') Function: Tests wether a feature contains a score Returns : TRUE if the SeqFeature has the score, and FALSE otherwise. Args : The name of a score =cut sub has_score { my ($self, $score) = @_; return undef unless defined $score; return exists $self->{'_gsf_score_hash'}->{$score}; } =head2 add_score_value Title : add_score_value Usage : $self->add_score_value('P_value',224); Returns : TRUE on success Args : score (string) and value (any scalar) =cut sub add_score_value { my ($self, $score, $value) = @_; if( ! defined $score || ! defined $value ) { $self->warn("must specify a valid $score and $value to add_score_value"); return 0; } if ( !defined $self->{'_gsf_score_hash'}->{$score} ) { $self->{'_gsf_score_hash'}->{$score} = []; } push(@{$self->{'_gsf_score_hash'}->{$score}},$value); } =head2 score Title : score Usage : $value = $comp_obj->score() $comp_obj->score($value) Function: Returns the 'default' score or sets the 'default' score This method exist for compatibility options It would equal ($comp_obj->each_score_value('default'))[0]; Returns : A value Args : (optional) a new value for the 'default' score =cut sub score { my ($self, $value) = @_; my @v; if (defined $value) { if( ref($value) =~ /HASH/i ) { while( my ($t,$val) = each %{ $value } ) { $self->add_score_value($t,$val); } } else { @v = $value; $self->add_score_value('default', $value); } } else { @v = $self->each_score_value('default'); } return $v[0]; } =head2 each_score_value Title : each_score_value Usage : @values = $gsf->each_score_value('note'); Function: Returns a list of all the values stored under a particular score. Returns : A list of scalars Args : The name of the score =cut sub each_score_value { my ($self, $score) = @_; if ( ! exists $self->{'_gsf_score_hash'}->{$score} ) { $self->warn("asking for score value that does not exist $score"); return undef; } return @{$self->{'_gsf_score_hash'}->{$score}}; } =head2 all_scores Title : all_scores Usage : @scores = $feat->all_scores() Function: Get a list of all the scores in a feature Returns : An array of score names Args : none =cut sub all_scores { my ($self, @args) = @_; return keys %{$self->{'_gsf_score_hash'}}; } =head2 remove_score Title : remove_score Usage : $feat->remove_score('some_score') Function: removes a score from this feature Returns : nothing Args : score (string) =cut sub remove_score { my ($self, $score) = @_; if ( ! exists $self->{'_gsf_score_hash'}->{$score} ) { $self->warn("trying to remove a score that does not exist: $score"); } delete $self->{'_gsf_score_hash'}->{$score}; } =head2 computation_id Title : computation_id Usage : $computation_id = $feat->computation_id() $feat->computation_id($computation_id) Function: get/set on program name information Returns : string Args : none if get, the new value if set =cut sub computation_id { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_computation_id'} = $value; } return $self->{'_gsf_computation_id'}; } =head2 program_name Title : program_name Usage : $program_name = $feat->program_name() $feat->program_name($program_name) Function: get/set on program name information Returns : string Args : none if get, the new value if set =cut sub program_name { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_program_name'} = $value; } return $self->{'_gsf_program_name'}; } =head2 program_date Title : program_date Usage : $program_date = $feat->program_date() $feat->program_date($program_date) Function: get/set on program date information Returns : date (string) Args : none if get, the new value if set =cut sub program_date { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_program_date'} = $value; } return $self->{'_gsf_program_date'}; } =head2 program_version Title : program_version Usage : $program_version = $feat->program_version() $feat->program_version($program_version) Function: get/set on program version information Returns : date (string) Args : none if get, the new value if set =cut sub program_version { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_program_version'} = $value; } return $self->{'_gsf_program_version'}; } =head2 database_name Title : database_name Usage : $database_name = $feat->database_name() $feat->database_name($database_name) Function: get/set on program name information Returns : string Args : none if get, the new value if set =cut sub database_name { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_database_name'} = $value; } return $self->{'_gsf_database_name'}; } =head2 database_date Title : database_date Usage : $database_date = $feat->database_date() $feat->database_date($database_date) Function: get/set on program date information Returns : date (string) Args : none if get, the new value if set =cut sub database_date { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_database_date'} = $value; } return $self->{'_gsf_database_date'}; } =head2 database_version Title : database_version Usage : $database_version = $feat->database_version() $feat->database_version($database_version) Function: get/set on program version information Returns : date (string) Args : none if get, the new value if set =cut sub database_version { my ($self,$value) = @_; if (defined($value)) { $self->{'_gsf_database_version'} = $value; } return $self->{'_gsf_database_version'}; } =head2 sub_SeqFeature_type Title : sub_SeqFeature_type Usage : $sub_SeqFeature_type = $feat->sub_SeqFeature_type() $feat->sub_SeqFeature_type($sub_SeqFeature_type) Function: sub_SeqFeature_type is automatically set when adding a sub_computation (sub_SeqFeature) to a computation object Returns : sub_SeqFeature_type (string) Args : none if get, the new value if set =cut sub sub_SeqFeature_type { my ($self, $value) = @_; if (defined($value)) { $self->{'_gsf_sub_SeqFeature_type'} = $value; } return $self->{'_gsf_sub_SeqFeature_type'}; } =head2 all_sub_SeqFeature_types Title : all_Sub_SeqFeature_types Usage : @all_sub_seqfeature_types = $comp->all_Sub_SeqFeature_types(); Function: Returns an array with all subseqfeature types Returns : An array Args : none =cut sub all_sub_SeqFeature_types { my ($self) = @_; return keys ( %{$self->{'gsf_sub_hash'}} ); } =head2 sub_SeqFeature Title : sub_SeqFeature('sub_feature_type') Usage : @feats = $feat->sub_SeqFeature(); @feats = $feat->sub_SeqFeature('sub_feature_type'); Function: Returns an array of sub Sequence Features of a specific type or, if the type is ommited, all sub Sequence Features Returns : An array Args : (optional) a sub_SeqFeature type (ie exon, pattern) =cut sub sub_SeqFeature { my ($self, $ssf_type) = @_; my (@return_array) = (); if ($ssf_type eq '') { #return all sub_SeqFeatures foreach (keys ( %{$self->{'gsf_sub_hash'}} )){ push @return_array, @{$self->{'gsf_sub_hash'}->{$_}}; } return @return_array; } else { if (defined ($self->{'gsf_sub_hash'}->{$ssf_type})) { return @{$self->{'gsf_sub_hash'}->{$ssf_type}}; } else { $self->warn("$ssf_type is not a valid sub SeqFeature type"); } } } =head2 add_sub_SeqFeature Title : add_sub_SeqFeature Usage : $feat->add_sub_SeqFeature($subfeat); $feat->add_sub_SeqFeature($subfeat,'sub_seqfeature_type') $feat->add_sub_SeqFeature($subfeat,'EXPAND') $feat->add_sub_SeqFeature($subfeat,'EXPAND','sub_seqfeature_type') Function: adds a SeqFeature into a specific subSeqFeature array. with no 'EXPAND' qualifer, subfeat will be tested as to whether it lies inside the parent, and throw an exception if not. If EXPAND is used, the parents start/end/strand will be adjusted so that it grows to accommodate the new subFeature, optionally a sub_seqfeature type can be defined. Returns : nothing Args : An object which has the SeqFeatureI interface : (optional) 'EXPAND' : (optional) 'sub_SeqFeature_type' =cut sub add_sub_SeqFeature{ my ($self,$feat,$var1, $var2) = @_; $var1 = '' unless( defined $var1); $var2 = '' unless( defined $var2); my ($expand, $ssf_type) = ('', $var1 . $var2); $expand = 'EXPAND' if ($ssf_type =~ s/EXPAND//); if ( !$feat->isa('Bio::SeqFeatureI') ) { $self->warn("$feat does not implement Bio::SeqFeatureI. Will add it anyway, but beware..."); } if($expand eq 'EXPAND') { $self->_expand_region($feat); } else { if ( !$self->contains($feat) ) { $self->throw("$feat is not contained within parent feature, and expansion is not valid"); } } $ssf_type = 'default' if ($ssf_type eq ''); if (!(defined ($self->{'gsf_sub_hash'}->{$ssf_type}))) { @{$self->{'gsf_sub_hash'}->{$ssf_type}} = (); } $feat->sub_SeqFeature_type($ssf_type); push @{$self->{'gsf_sub_hash'}->{$ssf_type}}, $feat; } =head2 flush_sub_SeqFeature Title : flush_sub_SeqFeature Usage : $sf->flush_sub_SeqFeature $sf->flush_sub_SeqFeature('sub_SeqFeature_type'); Function: Removes all sub SeqFeature or all sub SeqFeatures of a specified type (if you want to remove a more specific subset, take an array of them all, flush them, and add back only the guys you want) Example : Returns : none Args : none =cut sub flush_sub_SeqFeature { my ($self, $ssf_type) = @_; if ($ssf_type) { if ((defined ($self->{'gsf_sub_hash'}->{$ssf_type}))) { delete $self->{'gsf_sub_hash'}->{$ssf_type}; } else { $self->warn("$ssf_type is not a valid sub SeqFeature type"); } } else { $self->{'_gsf_sub_hash'} = {}; # zap the complete hash implicitly. } } 1;