Raw content of Bio::EnsEMBL::Compara::DBSQL::MemberAdaptor
package Bio::EnsEMBL::Compara::DBSQL::MemberAdaptor;
use strict;
use Bio::EnsEMBL::Compara::Member;
use Bio::EnsEMBL::Compara::Attribute;
use Bio::EnsEMBL::Compara::DBSQL::SequenceAdaptor;
use Bio::EnsEMBL::DBSQL::BaseAdaptor;
use Bio::EnsEMBL::Utils::Argument qw(rearrange);
use Bio::EnsEMBL::Utils::Exception qw(throw warning);
our @ISA = qw(Bio::EnsEMBL::DBSQL::BaseAdaptor);
=head2 list_internal_ids
Arg : None
Example :
Description:
Returntype :
Exceptions :
Caller :
=cut
sub list_internal_ids {
my $self = shift;
my ($name, $syn) = @{$self->tables->[0]};
my $sql = "SELECT ${syn}.${name}_id from ${name} ${syn}";
my $sth = $self->prepare($sql);
$sth->execute;
my $internal_id;
$sth->bind_columns(\$internal_id);
my @internal_ids;
while ($sth->fetch()) {
push @internal_ids, $internal_id;
}
$sth->finish;
return \@internal_ids;
}
=head2 fetch_by_dbID
Arg [1] : int $id
the unique database identifier for the feature to be obtained
Example : $feat = $adaptor->fetch_by_dbID(1234);
Description: Returns the Member created from the database defined by the
the id $id.
Returntype : Bio::EnsEMBL::Compara::Member
Exceptions : thrown if $id is not defined
Caller : general
=cut
sub fetch_by_dbID {
my ($self,$id) = @_;
unless(defined $id) {
$self->throw("fetch_by_dbID must have an id");
}
my ($name, $syn) = @{$self->tables->[0]};
#construct a constraint like 't1.table1_id = 1'
my $constraint = "${syn}.${name}_id = $id";
#return first element of _generic_fetch list
my ($obj) = @{$self->_generic_fetch($constraint)};
return $obj;
}
sub fetch_by_dbIDs {
my $self = shift;
my $ids = join(',' , @_);
my $constraint = "m.member_id in ($ids)";
return $self->_generic_fetch($constraint);
}
=head2 fetch_by_source_stable_id
Arg [1] : (optional) string $source_name
Arg [2] : string $stable_id
Example : my $member = $ma->fetch_by_source_stable_id(
"Uniprot/SWISSPROT", "O93279");
Example : my $member = $ma->fetch_by_source_stable_id(
undef, "O93279");
Description: Fetches the member corresponding to this $stable_id.
Although two members from different sources might
have the same stable_id, this never happens in a normal
compara DB. You can set the first argument to undef
like in the second example.
Returntype : Bio::EnsEMBL::Compara::Member object
Exceptions : throws if $stable_id is undef
Caller :
=cut
sub fetch_by_source_stable_id {
my ($self,$source_name, $stable_id) = @_;
unless(defined $stable_id) {
throw("fetch_by_source_stable_id must have an stable_id");
}
# my $source_id = $self->get_source_id_from_name($source_name);
#construct a constraint like 't1.table1_id = 1'
my $constraint = "";
$constraint = "m.source_name = '$source_name' AND " if ($source_name);
$constraint .= "m.stable_id = '$stable_id'";
#return first element of _generic_fetch list
my ($obj) = @{$self->_generic_fetch($constraint)};
return $obj;
}
=head2 fetch_all
Arg : None
Example : my $members = $ma->fetch_all;
Description: Fetch all the members in the db
Returntype : listref of Bio::EnsEMBL::Compara::Member objects
Exceptions :
Caller :
=cut
sub fetch_all {
my $self = shift;
return $self->_generic_fetch();
}
=head2 fetch_by_source
DEPRECATED: use fetch_all_by_source instead
=cut
sub fetch_by_source {
my ($self, @args) = @_;
return $self->fetch_all_by_source(@args);
}
=head2 fetch_all_by_source
Arg [1] : string $source_name
Example : my $members = $ma->fetch_all_by_source(
"Uniprot/SWISSPROT");
Description: Fetches the member corresponding to a source_name.
Returntype : listref of Bio::EnsEMBL::Compara::Member objects
Exceptions : throws if $source_name is undef
Caller :
=cut
sub fetch_all_by_source {
my ($self,$source_name) = @_;
$self->throw("source_name arg is required\n")
unless ($source_name);
# my $source_id = $self->get_source_id_from_name($source_name);
my $constraint = "m.source_name = '$source_name'";
return $self->_generic_fetch($constraint);
}
=head2 fetch_by_source_taxon
DEPRECATED: use fetch_all_by_source_taxon instead
=cut
sub fetch_by_source_taxon {
my ($self, @args) = @_;
return $self->fetch_all_by_source_taxon(@args);
}
=head2 fetch_all_by_source_taxon
Arg [1] : string $source_name
Arg [2] : int $taxon_id
Example : my $members = $ma->fetch_all_by_source_taxon(
"Uniprot/SWISSPROT", 9606);
Description: Fetches the member corresponding to a source_name and a taxon_id.
Returntype : listref of Bio::EnsEMBL::Compara::Member objects
Exceptions : throws if $source_name or $taxon_id is undef
Caller :
=cut
sub fetch_all_by_source_taxon {
my ($self,$source_name,$taxon_id) = @_;
$self->throw("source_name and taxon_id args are required")
unless($source_name && $taxon_id);
# my $source_id = $self->get_source_id_from_name($source_name);
my $constraint = "m.source_name = '$source_name' and m.taxon_id = $taxon_id";
return $self->_generic_fetch($constraint);
}
=head2 get_source_taxon_count
Arg [1] : string $source_name
Arg [2] : int $taxon_id
Example : my $sp_gene_count = $memberDBA->get_source_taxon_count('ENSEMBLGENE',$taxon_id);
Description:
Returntype : int $sp_gene_count is the number of members for this source_name and taxon_id
Exceptions :
Caller :
=cut
sub get_source_taxon_count {
my ($self,$source_name,$taxon_id) = @_;
$self->throw("source_name and taxon_id args are required")
unless($source_name && $taxon_id);
my $sth = $self->prepare
("SELECT COUNT(*) FROM member WHERE source_name=? AND taxon_id=?");
$sth->execute($source_name, $taxon_id);
my ($count) = $sth->fetchrow_array();
$sth->finish;
return $count;
}
=head2 fetch_by_relation
DEPRECATED: use fetch_all_by_relation instead
=cut
sub fetch_by_relation {
my ($self, @args) = @_;
return $self->fetch_all_by_relation(@args);
}
=head2 fetch_all_by_relation
Arg [1] :
Example :
Description:
Returntype :
Exceptions :
Caller :
=cut
sub fetch_all_by_relation {
my ($self, $relation) = @_;
my $join;
my $constraint;
$self->throw()
unless (defined $relation && ref $relation);
if ($relation->isa('Bio::EnsEMBL::Compara::Family')) {
my $family_id = $relation->dbID;
$constraint = "fm.family_id = $family_id";
my $extra_columns = [qw(fm.family_id
fm.member_id
fm.cigar_line)];
$join = [[['family_member', 'fm'], 'm.member_id = fm.member_id', $extra_columns]];
}
elsif ($relation->isa('Bio::EnsEMBL::Compara::Domain')) {
my $domain_id = $relation->dbID;
$constraint = "dm.domain_id = $domain_id";
my $extra_columns = [qw(dm.domain_id
dm.member_id
dm.member_start
dm.member_end)];
$join = [[['domain_member', 'dm'], 'm.member_id = dm.member_id', $extra_columns]];
}
elsif ($relation->isa('Bio::EnsEMBL::Compara::Homology')) {
my $homology_id = $relation->dbID;
$constraint .= "hm.homology_id = $homology_id";
my $extra_columns = [qw(hm.homology_id
hm.member_id
hm.peptide_member_id
hm.peptide_align_feature_id
hm.cigar_line
hm.cigar_start
hm.cigar_end
hm.perc_cov
hm.perc_id
hm.perc_pos)];
$join = [[['homology_member', 'hm'], 'm.member_id = hm.member_id', $extra_columns]];
}
else {
$self->throw();
}
return $self->_generic_fetch($constraint, $join);
}
=head2 fetch_by_relation_source
DEPRECATED: use fetch_all_by_relation_source instead
=cut
sub fetch_by_relation_source {
my ($self, @args) = @_;
return $self->fetch_all_by_relation_source(@args);
}
=head2 fetch_all_by_relation_source
Arg [1] :
Example :
Description:
Returntype :
Exceptions :
Caller :
=cut
sub fetch_all_by_relation_source {
my ($self, $relation, $source_name) = @_;
$self->throw()
unless (defined $relation && ref $relation);
$self->throw("source_name arg is required\n")
unless ($source_name);
my $join;
# my $source_id = $self->get_source_id_from_name($source_name);
my $constraint = "m.source_name = '$source_name'";
if ($relation->isa('Bio::EnsEMBL::Compara::Family')) {
my $family_id = $relation->dbID;
$constraint .= " AND fm.family_id = $family_id";
my $extra_columns = [qw(fm.family_id
fm.member_id
fm.cigar_line)];
$join = [[['family_member', 'fm'], 'm.member_id = fm.member_id', $extra_columns]];
}
elsif ($relation->isa('Bio::EnsEMBL::Compara::Domain')) {
my $domain_id = $relation->dbID;
$constraint .= " AND dm.domain_id = $domain_id";
my $extra_columns = [qw(dm.domain_id
dm.member_id
dm.member_start
dm.member_end)];
$join = [[['domain_member', 'dm'], 'm.member_id = dm.member_id', $extra_columns]];
}
elsif ($relation->isa('Bio::EnsEMBL::Compara::Homology')) {
my $homology_id = $relation->dbID;
$constraint .= " AND hm.homology_id = $homology_id";
my $extra_columns = [qw(hm.homology_id
hm.member_id
hm.peptide_member_id
hm.peptide_align_feature_id
hm.cigar_line
hm.cigar_start
hm.cigar_end
hm.perc_cov
hm.perc_id
hm.perc_pos)];
$join = [[['homology_member', 'hm'], 'm.member_id = hm.member_id', $extra_columns]];
}
else {
$self->throw();
}
return $self->_generic_fetch($constraint, $join);
}
=head2 fetch_by_relation_source_taxon
DEPRECATED: use fetch_all_by_relation_source_taxon instead
=cut
sub fetch_by_relation_source_taxon {
my ($self, @args) = @_;
return $self->fetch_all_by_relation_source_taxon(@args);
}
=head2 fetch_all_by_relation_source_taxon
Arg [1] :
Example :
Description:
Returntype :
Exceptions :
Caller :
=cut
sub fetch_all_by_relation_source_taxon {
my ($self, $relation, $source_name, $taxon_id) = @_;
$self->throw()
unless (defined $relation && ref $relation);
$self->throw("source_name and taxon_id args are required")
unless($source_name && $taxon_id);
my $join;
# my $source_id = $self->get_source_id_from_name($source_name);
my $constraint = "m.source_name = '$source_name' AND m.taxon_id = $taxon_id";
if ($relation->isa('Bio::EnsEMBL::Compara::Family')) {
my $family_id = $relation->dbID;
$constraint .= " AND fm.family_id = $family_id";
my $extra_columns = [qw(fm.family_id
fm.member_id
fm.cigar_line)];
$join = [[['family_member', 'fm'], 'm.member_id = fm.member_id', $extra_columns]];
}
elsif ($relation->isa('Bio::EnsEMBL::Compara::Domain')) {
my $domain_id = $relation->dbID;
$constraint .= " AND dm.domain_id = $domain_id";
my $extra_columns = [qw(dm.domain_id
dm.member_id
dm.member_start
dm.member_end)];
$join = [[['domain_member', 'dm'], 'm.member_id = dm.member_id', $extra_columns]];
}
# elsif ($relation->isa('Bio::EnsEMBL::Compara::Homology')) {
# }
else {
$self->throw();
}
return $self->_generic_fetch($constraint, $join);
}
=head2 fetch_by_subset_id
DEPRECATED: use fetch_all_by_subset_id instead
=cut
sub fetch_by_subset_id {
my ($self, @args) = @_;
return $self->fetch_all_by_subset_id(@args);
}
=head2 fetch_all_by_subset_id
Arg [1] : int subset_id
Example : @members = @{$memberAdaptor->fetch_all_by_subset_id($subset_id)};
Description: given a subset_id, does a join to the subset_member table
to return a list of Member objects in this subset
Returntype : list by reference of Compara::Member objects
Exceptions :
Caller : general
=cut
sub fetch_all_by_subset_id {
my ($self, $subset_id) = @_;
$self->throw() unless (defined $subset_id);
my $constraint = "sm.subset_id = '$subset_id'";
my $join = [[['subset_member', 'sm'], 'm.member_id = sm.member_id']];
return $self->_generic_fetch($constraint, $join);
}
=head2 fetch_gene_for_peptide_member_id
Arg [1] : int member_id of a peptide member
Example : $geneMember = $memberAdaptor->fetch_gene_for_peptide_member_id($peptide_member_id);
Description: given a member_id of a peptide member,
does a join to a copy of member table to extract a member for its gene
Returntype : Bio::EnsEMBL::Compara::Member object
Exceptions :
Caller : general
=cut
sub fetch_gene_for_peptide_member_id {
my ($self, $peptide_member_id) = @_;
$self->throw() unless (defined $peptide_member_id);
my $constraint = "pepm.member_id = '$peptide_member_id'";
my $join = [[['member', 'pepm'], 'm.member_id = pepm.gene_member_id']];
my $obj = undef;
eval {
($obj) = @{$self->_generic_fetch($constraint, $join)};
};
return $obj;
}
=head2 fetch_all_peptides_for_gene_member_id
DEPRECATED: use fetch_all_peptides_for_gene_member_id instead
=cut
sub fetch_peptides_for_gene_member_id {
my ($self, @args) = @_;
return $self->fetch_all_peptides_for_gene_member_id(@args);
}
=head2 fetch_all_peptides_for_gene_member_id
Arg [1] : int member_id of a gene member
Example : @pepMembers = @{$memberAdaptor->fetch_all_peptides_for_gene_member_id($gene_member_id)};
Description: given a member_id of a gene member,
fetches all peptide members for this gene
Returntype : array ref of Bio::EnsEMBL::Compara::Member objects
Exceptions :
Caller : general
=cut
sub fetch_all_peptides_for_gene_member_id {
my ($self, $gene_member_id) = @_;
$self->throw() unless (defined $gene_member_id);
my $constraint = "m.gene_member_id = '$gene_member_id'";
my $peplist = undef;
eval {
$peplist = $self->_generic_fetch($constraint);
};
return $peplist;
}
=head2 fetch_longest_peptide_member_for_gene_member_id
Arg [1] : int member_id of a gene member
Example : $pepMembers = $memberAdaptor->fetch_peptides_for_gene_member_id($gene_member_id);
Description: given a member_id of a gene member,
fetches all peptide members for this gene
Returntype : Bio::EnsEMBL::Compara::Member object
Exceptions :
Caller : general
=cut
sub fetch_longest_peptide_member_for_gene_member_id {
my ($self, $gene_member_id) = @_;
$self->throw() unless (defined $gene_member_id);
my $constraint = "m.gene_member_id = '$gene_member_id'";
my $join = [[['sequence', 'seq'], 'm.sequence_id = seq.sequence_id']];
my $sql_tmp = "ORDER BY seq.length DESC, member_id ";
my $new_sql = $self->dbc->add_limit_clause($sql_tmp,1);
$self->_final_clause($new_sql);
# $self->_final_clause("ORDER BY seq.length DESC, member_id LIMIT 1");
#fixed fetch_longest_peptide_member_for_gene_member_id so that it returns
#the same longest peptide used in the peptide_align_feature. There are some
#cases where a gene will have multiple transcripts but with the same translation
#sequence (and hence the same sequence length). The code that picks the longest
#in the production pipeline uses a > test so the first translation that hits
#the longest length will be the one picked. Since the insert is done right away
#the member with the smallest member_id (of the equal length translations) is the
#one picked as 'longest' for use in the blasting.
#so "ORDER BY seq.length DESC, member_id LIMIT 1" picks the right one.
#Yeah it is a hack, but it does work.
my $obj = undef;
eval {
($obj) = @{$self->_generic_fetch($constraint, $join)};
};
$self->_final_clause("");
return $obj;
}
#
# INTERNAL METHODS
#
###################
=head2 _generic_fetch
Arg [1] : (optional) string $constraint
An SQL query constraint (i.e. part of the WHERE clause)
Arg [2] : (optional) string $logic_name
the logic_name of the analysis of the features to obtain
Example : $fts = $a->_generic_fetch('contig_id in (1234, 1235)', 'Swall');
Description: Performs a database fetch and returns feature objects in
contig coordinates.
Returntype : listref of Bio::EnsEMBL::SeqFeature in contig coordinates
Exceptions : none
Caller : BaseFeatureAdaptor, ProxyDnaAlignFeatureAdaptor::_generic_fetch
=cut
sub _generic_fetch {
my ($self, $constraint, $join) = @_;
my @tables = @{$self->tables};
my $columns = join(', ', @{$self->columns()});
if ($join) {
foreach my $single_join (@{$join}) {
my ($tablename, $condition, $extra_columns) = @{$single_join};
if ($tablename && $condition) {
push @tables, $tablename;
if($constraint) {
$constraint .= " AND $condition";
} else {
$constraint = " $condition";
}
}
if ($extra_columns) {
$columns .= ", " . join(', ', @{$extra_columns});
}
}
}
#construct a nice table string like 'table1 t1, table2 t2'
my $tablenames = join(', ', map({ join(' ', @$_) } @tables));
my $sql = "SELECT $columns FROM $tablenames";
my $default_where = $self->_default_where_clause;
my $final_clause = $self->_final_clause;
#append a where clause if it was defined
if($constraint) {
$sql .= " WHERE $constraint ";
if($default_where) {
$sql .= " AND $default_where ";
}
} elsif($default_where) {
$sql .= " WHERE $default_where ";
}
#append additional clauses which may have been defined
$sql .= " $final_clause" if($final_clause);
#print("$sql\n");
my $sth = $self->prepare($sql);
$sth->execute;
# print STDERR $sql,"\n";
return $self->_objs_from_sth($sth);
}
sub tables {
return [['member', 'm']];
}
sub columns {
return ['m.member_id',
'm.source_name',
'm.stable_id',
'm.version',
'm.taxon_id',
'm.genome_db_id',
'm.description',
'm.chr_name',
'm.chr_start',
'm.chr_end',
'm.chr_strand',
'm.sequence_id',
'm.gene_member_id',
'm.display_label'
];
}
sub create_instance_from_rowhash {
my ($self, $rowhash) = @_;
return Bio::EnsEMBL::Compara::Member->new_fast({
_dbID => $rowhash->{member_id},
_stable_id => $rowhash->{stable_id},
_version => $rowhash->{version},
_taxon_id => $rowhash->{taxon_id},
_genome_db_id => $rowhash->{genome_db_id},
_description => $rowhash->{description},
_chr_name => $rowhash->{chr_name},
_chr_start => $rowhash->{chr_start},
_chr_end => $rowhash->{chr_end},
_chr_strand => $rowhash->{chr_strand},
_sequence_id => $rowhash->{sequence_id} || 0,
_source_name => $rowhash->{source_name},
_display_label => $rowhash->{display_label},
_gene_member_id => $rowhash->{gene_member_id},
_adaptor => $self
});
}
sub init_instance_from_rowhash {
my $self = shift;
my $member = shift;
my $rowhash = shift;
$member->member_id($rowhash->{'member_id'});
$member->stable_id($rowhash->{'stable_id'});
$member->version($rowhash->{'version'});
$member->taxon_id($rowhash->{'taxon_id'});
$member->genome_db_id($rowhash->{'genome_db_id'});
$member->description($rowhash->{'description'});
$member->chr_name($rowhash->{'chr_name'});
$member->chr_start($rowhash->{'chr_start'});
$member->chr_end($rowhash->{'chr_end'});
$member->chr_strand($rowhash->{'chr_strand'});
$member->sequence_id($rowhash->{'sequence_id'});
$member->gene_member_id($rowhash->{'gene_member_id'});
$member->source_name($rowhash->{'source_name'});
$member->display_label($rowhash->{'display_label'});
$member->adaptor($self);
return $member;
}
sub _objs_from_sth {
my ($self, $sth) = @_;
my @members = ();
while(my $rowhash = $sth->fetchrow_hashref) {
my ($member,$attribute);
$member = $self->create_instance_from_rowhash($rowhash);
my @_columns = @{$self->columns};
if (scalar keys %{$rowhash} > scalar @_columns) {
$attribute = new Bio::EnsEMBL::Compara::Attribute;
$attribute->member_id($rowhash->{'member_id'});
foreach my $autoload_method (keys %$rowhash) {
next if (grep /$autoload_method/, @_columns);
$attribute->$autoload_method($rowhash->{$autoload_method});
}
}
if (defined $attribute) {
push @members, [$member, $attribute];
} else {
push @members, $member;
}
}
$sth->finish;
return \@members
}
sub _default_where_clause {
my $self = shift;
return '';
}
sub _final_clause {
my $self = shift;
$self->{'_final_clause'} = shift if(@_);
return $self->{'_final_clause'};
}
sub _fetch_sequence_by_id {
my ($self, $sequence_id) = @_;
return $self->db->get_SequenceAdaptor->fetch_by_dbID($sequence_id);
}
sub create_AlignedMember_from_member_attribute {
my $self = shift;
my $member_attribute = shift;
my ($gene_member, $attribute) = @{$member_attribute};
my $member = $self->fetch_by_dbID($attribute->peptide_member_id);
bless $member, "Bio::EnsEMBL::Compara::AlignedMember";
$member->cigar_line($attribute->cigar_line);
$member->cigar_start($attribute->cigar_start);
$member->cigar_end($attribute->cigar_end);
$member->adaptor(undef);
return $member;
}
#
# STORE METHODS
#
################
=head2 store
Arg [1] :
Example :
Description:
Returntype :
Exceptions :
Caller :
=cut
sub store {
my ($self,$member) = @_;
unless($member->isa('Bio::EnsEMBL::Compara::Member')) {
$self->throw(
"member arg must be a [Bio::EnsEMBL::Compara::Member]"
. "not a $member");
}
# $member->source_id($self->store_source($member->source_name));
my $sth = $self->prepare("INSERT ignore INTO member (stable_id,version, source_name,
taxon_id, genome_db_id, description,
chr_name, chr_start, chr_end, chr_strand,display_label)
VALUES (?,?,?,?,?,?,?,?,?,?,?)");
my $insertCount = $sth->execute($member->stable_id,
$member->version,
$member->source_name,
$member->taxon_id,
$member->genome_db_id,
$member->description,
$member->chr_name,
$member->chr_start,
$member->chr_end,
$member->chr_strand,
$member->display_label);
if($insertCount>0) {
#sucessful insert
$member->dbID( $sth->{'mysql_insertid'} );
$sth->finish;
} else {
$sth->finish;
#UNIQUE(source_id,stable_id) prevented insert since member was already inserted
#so get member_id with select
my $sth2 = $self->prepare("SELECT member_id, sequence_id FROM member WHERE source_name=? and stable_id=?");
$sth2->execute($member->source_name, $member->stable_id);
my($id, $sequence_id) = $sth2->fetchrow_array();
warn("MemberAdaptor: insert failed, but member_id select failed too") unless($id);
$member->dbID($id);
$member->sequence_id($sequence_id) if ($sequence_id);
$sth2->finish;
}
$member->adaptor($self);
# insert in sequence table to generate new
# sequence_id to insert into member table;
if(defined($member->sequence) and $member->sequence_id == 0) {
$member->sequence_id($self->db->get_SequenceAdaptor->store($member->sequence));
my $sth3 = $self->prepare("UPDATE member SET sequence_id=? WHERE member_id=?");
$sth3->execute($member->sequence_id, $member->dbID);
$sth3->finish;
}
return $member->dbID;
}
sub update_sequence {
my ($self, $member) = @_;
return 0 unless($member);
unless($member->dbID) {
throw("MemberAdapter::update_sequence member must have valid dbID\n");
}
unless(defined($member->sequence)) {
warning("MemberAdapter::update_sequence with undefined sequence\n");
}
if($member->sequence_id) {
my $sth = $self->prepare("UPDATE sequence SET sequence = ?, length=? WHERE sequence_id = ?");
$sth->execute($member->sequence, $member->seq_length, $member->sequence_id);
$sth->finish;
} else {
$member->sequence_id($self->db->get_SequenceAdaptor->store($member->sequence));
my $sth3 = $self->prepare("UPDATE member SET sequence_id=? WHERE member_id=?");
$sth3->execute($member->sequence_id, $member->dbID);
$sth3->finish;
}
return 1;
}
sub store_gene_peptide_link {
my ($self, $gene_member_id, $peptide_member_id) = @_;
eval {
my $sth = $self->prepare("UPDATE member SET gene_member_id=? where member_id=?");
$sth->execute($gene_member_id, $peptide_member_id);
$sth->finish;
};
}
1;