| AAChange | Sequence change class for polypeptides |
| AAReverseMutate | point mutation and codon information from single amino acid changes |
| Allele | Sequence object with allele-specific attributes |
| DNAMutation | DNA level mutation class |
| IO | Handler for sequence variation IO Formats |
| RNAChange | Sequence change class for RNA level |
| SNP | submitted SNP |
| SeqDiff | Container class for mutation/variant descriptions |
| VariantI | Sequence Change SeqFeature abstract class |